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Handary S.A. is seeking an experienced Nisin Production Scientist / Bioprocess Engineer to support the development, commissioning and operation of our nisin production line in fleurus, Belgium.

Tasks & Responsabilities:

Develop and optimise nisin fermentation and downstream purification processes.
Operate bioreactors, centrifugation, filtration, ÄKTA ready, ÄKTA flux and chromatography systems.
Establish process parameters for fermentation, recovery, concentration, purification and formulation.
Improve yield, purity, biological activity and batch-to-batch consistency.
Develop analytical methods for nisin identification, potency, purity and stability.
Prepare SOPs, batch records, validation protocols and technical reports.
Train production and laboratory personnel.
Support scale-up from laboratory trials to pilot and industrial production.
Ensure compliance with applicable food-safety, quality and GMP requirements.

Requirements

Ph.D., MSc or equivalent experience in biotechnology, biochemical engineering, fermentation science, microbiology or a related field.
Practical experience in microbial fermentation and protein or peptide purification.
Experience with Lactococcus lactis, bacteriocins or nisin production is strongly preferred.
Familiarity with tangential-flow filtration, chromatography and ÄKTA equipment.
Strong understanding of process development, scale-up, contamination control and analytical validation.
Able to work independently and solve practical production problems.
Professional English is required; French is an advantage.

Engagement

The position may be arranged on a full-time, part-time or consultancy basis, depending on the candidate’s availability and experience.

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